Dovato (dolutegravir and lamivudine) is a combination antiviral medication that prevents human immunodeficiency virus (HIV) from multiplying in your body. Dovato is a complete regimen for the treatment of HIV infection and should not be used with other HIV medications. It is used to prevent the spread of HIV and the development of acquired immunodeficiency syndrome (AIDS). Dovato is not a cure for HIV or AIDS. Dovato is only for use in adults who have not been treated with other antiviral medications before. Dolutegravir and lamivudine are both enzyme inhibitors. Dolutegravir blocks the integrase enzymes, while lamivudine blocks reverse transcriptase enzymes. These enzymes are needed by HIV to multiply and grow, so by blocking them, Dovato prevents the spread of HIV and can reduce the amount of HIV in the body. Dovato will not prevent your disease from spreading. You should not have unprotected sex, or share razors or toothbrushes. Tell your doctor if you have ever had hepatitis B, as Dovato can cause it to become active again or worsen. As well, tell your doctor about any medications you are currently taking in order to reduce the risk of interactions. If you experience any serious side effects or signs of an allergic reaction, seek emergency medical attention.
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