Janumet XR (Sitagliptin/Metformin XR) is used to treat high blood sugar with type 2 diabetes. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Janumet XR is a combination of two medications: Sitagliptin and Metformin. Sitagliptin works by increasing levels of natural substances called incretins, whereas metformin works by helping to restore your body’s proper response to the insulin you naturally produce. Janumet XR helps prevent kidney damage, blindness, nerve problems, loss of limbs and sexual function problems. This medication works by helping your pancreas effectively create and use more insulin and decreases the excess sugar that your liver makes. Do not take this medication if you are allergic. Talk to your medical professional if you have a history of kidney disease, severe breathing problems (such as obstructive lung disease, severe asthma), liver disease, a disease of the pancreas (pancreatitis) or stones in your gallbladder (gallstones). Take this medication as directed by your doctor. Consult your doctor for any possible side effects and precautions. If you experience any serious side effects, contact your doctor promptly.
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