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Home > Drug Category > Irritable Bowel Syndrome > Ibsrela and Equivalent

Ibsrela Information

Ibsrela (Tenapanor Hydrochloride) is a medication used to treat irritable bowel syndrome with constipation (IBS-C). Irritable bowel syndrome with constipation (IBS-C) is a condition in which the normal functioning of the gastrointestinal tract is impaired with no structural abnormalities that can be found with an endoscope (a flexible viewing tube). Affected people usually complain of cramping, abdominal pain, bloating, gas, diarrhea, or constipation. Sodium/hydrogen ion exchanger 3 (NHE3) inhibitors like Ibsrela decrease the amount of sodium the bowels absorb, increasing the amount of fluid in the bowels. This action causes the stool to be softer, so the material in the intestines and colon can pass through the digestive system more quickly, thereby increasing the number of bowel movements and helping to ease stomach pain. It is unknown if Ibsrela is safe and effective in children less than 18 years of age.

Ibsrela Side Effects

The most common side effects of Ibsrela may include diarrhea; swelling, a feeling of fullness in your abdomen (distension), gas (flatulence), or dizziness. Call your doctor right away if you have any of the serious side effects such as:
• Bleeding per rectum;
• Dizziness;
• Difficulty in passing stool (impacted feces);
• Feeling weak or passing out;
• Passaged of blood-stained stool or dark colour stool;
• Severe diarrhea that doesn’t stop;
• Worsening of your condition

Ibsrela Precautions

Do not take the Ibsrela tablet without discussing with your doctor or pharmacist if you are allergic to it or any ingredients. Before you start taking this medication, tell your doctor about your medical history, including if you are allergic to Tenapanor or any ingredients of the medication, have intestinal obstruction; liver disease, kidney disease; intestinal perforation; children aged <6 years, and inflammatory bowel diseases including chron’s disease and ulcerative colitis. Do not give this medication to a child. It comes as a tablet and should be taken according to your doctor’s prescription. Do not use more than your prescribed dosage. The tablet should be taken orally with a cup of water, usually twice daily: immediately before your first meal and once before dinner. Swallow the tablets whole. Do not crush or chew the tablets. Ibsrela is most effective when it is taken right before you start eating. Ibsrela should not be given to patients 6 years to less than 18 years of age. Continue to use this medication at the prescribed dose until your doctor says otherwise. It is often recommended to drink enough water when using Ibsrela medicine and talk to your doctor if you have a complaint about your treatment. Inform your doctor if your condition worsens or there is no significant improvement despite regular use of the Ibsrela tablet. There may be a drug interaction between Ibsrela and other medications such as atorvastatin, influenzas, Fluvastatin, furosemide, pravastatin, and enalapril. Inform your doctor if you are pregnant, plan to become pregnant, or breastfeeding a baby. It is unknown if Ibsrela will harm your unborn baby. Breastfeeding or plan to breastfeed. It is not known if Ibsrela passes into your breast milk. Talk with your doctor about how to feed your baby if you take Ibsrela.

Do I need a prescription to order Ibsrela?

Yes, a prescription is required from your physician to order Ibsrela.