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Home > Drug Category > Diabetic Medications and Products > Komboglyze and Equivalent

Komboglyze Information

Komboglyze (Saxagliptin/Metformin) is used to control blood sugar. Hyperglycemia, also known as high blood sugar, can occur due to a sedentary lifestyle, poor diet, stress, and hormonal changes. Certain medications can also increase blood sugar levels. The active ingredients in Komboglyze are Saxagliptin and Metformin. DPP-4 inhibitors like Saxagliptin work by increasing the amount of incretin, a hormone that raises insulin levels when blood sugar is high and decreases the amount of sugar made by the body released by the intestine. Hypoglycemics like metformin work by stimulating the pancreas to produce insulin.

Komboglyze Side Effects

The most common side effects of Komboglyze may include appetite loss, headache, gas, constipation, and tiredness. Call your doctor right away if you have any of the serious side effects, such as:
• Severe and persistent stomach pain;
• Severe joint pain;
• Signs of an allergic reaction, such as rash, breathing difficulties, itching or swelling of the face, tongue, or throat;
• Signs of lactic acidosis such as muscle cramps, vomiting, stomach ache, reduced body temperature

Komboglyze Precautions

Do not use Komboglyze if you are allergic to Saxagliptin, Metformin, or other ingredients in this medication. Before you start using this medication, tell your doctor about your medical history, including if you have a history of lactic acidosis, dehydration, diabetic coma, heart problems, liver disease, type 1 diabetes, think you may be pregnant, or plan to become pregnant, are breastfeeding, or are planning to breastfeed. Tell your doctor about all your medications, including prescription, OTC, herbal supplements, and vitamins. There may be a drug interaction between Komboglyze and other medications, such as ketoconazole, cimetidine, carbamazepine, ibuprofen, phenytoin, rifampicin, diltiazem, etc. Do not use Komboglyze if you are pregnant or planning to become pregnant without informing your doctor. Komboglyze may harm a fetus. Do not use Komboglyze while breastfeeding without talking to your doctor. Metformin passes into breast milk in trace amounts. Do not give this drug to children below 18 years without talking to your doctor. Use your medicine exactly as prescribed by your doctor. Take this drug by mouth with food to reduce your risk of stomach upset. To control your diabetes, you still need to diet and exercise, even when you are taking this medicine. Do not stop taking this drug suddenly without talking to your doctor. The drug is supposed to keep your blood sugar under control. Avoid drinking alcohol when using this drug. Alcohol can increase your risk of developing lactic acidosis. Your doctor will check your kidney function during treatment with this medicine. Store this medication at room temperature, away from moisture and heat. Keep it out of the reach of children.

Do I need a prescription to order Komboglyze?

Yes, a prescription is required from your physician to order Komboglyze.