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Home > Drug Category > Asthma Medication/ Respiratory Disorders > Nucala and Equivalent

Nucala Information

Nucala (Mepolizumab) is a prescription medication used to treat adults and children (age six and older) with severe eosinophilic asthma, a form of severe asthma. Nucala powder for injection is also used with other medicines to treat nasal polyps and chronic rhinosinusitis. The active substance in Nucala is Mepolizumab. Mepolizumab belongs to the class of medication called Interleukin Inhibitors, which are monoclonal antibodies (Anti-asthmatics). It reduces the level of eosinophils by preventing the binding of IL-5 to eosinophils. This reduces blood, tissue, and sputum eosinophil levels. It would be best to know that Nucala is not for acute bronchospasm or status asthmaticus relief. Talk to your doctor for a quick relief inhaler or medication.

Nucala Side Effects

The most common side effects of Nucala may include headache, pain, redness, swelling, itching, a burning feeling at the injection site, back pain, and tiredness.

Call your doctor right away if you have any of the severe side effects such as:
• Burning or tingling anywhere in your body;
• Symptoms of an allergic reaction include swelling of your face, mouth, and tongue, breathing problems, fainting, dizziness, feeling lightheaded;
• Unusual pain or tiredness

Nucala Precautions

Before you start using Nucala injection, you should inform your doctor if you are allergic to Mepolizumab or any of the ingredients in Nucala. In addition, tell your doctor if you are taking oral or inhaled corticosteroid medicines. Do not stop taking your other asthma medicines, including your corticosteroid medicines, unless instructed by your doctor because this may worsen your symptoms. Nucala comes as a powder for injection. It is reconstituted with a diluent and injected under the skin, usually once every four weeks. Your doctor may teach you how to use the injection at home properly. You should ask your doctor if you do not understand something. Seek medical attention if your breathing problems get worse or if you think your asthma medications are not working as expected. Before you start using this medication, tell your doctor about your medical history; if you have herpes zoster infection, kidney problem, liver disease (hepatitis or cirrhosis), and parasitic infections. Inform your doctor if you are pregnant, think you may be pregnant, or plan to become pregnant. Mepolizumab may harm your child, especially during the second trimester. Your doctor will discuss the benefits and potential risks of being given this medicine during pregnancy. In addition, it is unknown whether the active ingredients of Nucala can pass into breast milk. Nucala has no known drug interaction, however, do not use other similar medication with Nucala medicine. Store this medication out of reach of children.

Do I need a prescription to order Nucala?

Yes, a prescription is required from your physician to order Nucala.