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Home > Drug Category > AIDS Medications, HIV Treatments > Prezcobix and Equivalent

Prezcobix Information

Prezcobix (Darunavir Ethanolate/Cobicistat) is used with other Human Immunodeficiency Virus Type 1 (HIV-1) medicines to treat HIV-1 infection in adults and children who weigh at least 88 pounds (40 kg). HIV-1 is the virus that causes Acquired Immune Deficiency Syndrome (AIDS). HIV damages the immune system, so the body is less able to fight infection and disease. Prezcobix is a combination medicine containing Darunavir Ethanolate and Cobicistat. Protease inhibitors like Darunavir Ethanolate prevent the replication of HIV by stopping the formation of mature virus particles. Pharmacokinetic boosters like Cobicistat increase the amount of Darunavir in the body to have a more significant effect. Prezcobix is not a cure for HIV or AIDS.

Prezcobix Side Effects

The most common side effects of Prezcobix may include diarrhea, nausea, rash, headache, and vomiting. Call your doctor right away if you have any of the serious side effects, such as:
• Changes in body fat;
• Signs of a new infection, such as fever, night sweats, cold sores, wheezing, weight loss;
• Signs of an allergic reaction, such as rash, breathing difficulties, itching or swelling of the face, tongue, or throat;
• Signs of high blood sugar, such as increased thirst, increased urination, fruity breath odor, blurred vision;
• Signs of liver problems, such as upper stomach pain, loss of appetite, clay-colored stools, dark urine

Prezcobix Precautions

Do not use Prezcobix if you are allergic to Darunavir Ethanolate, Cobicistat, or other ingredients in this medication. Before you start using this medication, tell your doctor about your medical history, including if you have Liver disease, Kidney disease, A bleeding or blood clotting disorder, Diabetes, Are allergic to sulfa drugs, think you may be pregnant, or plan to become pregnant, are breastfeeding, or are planning to breastfeed. Tell your doctor about all your medications, including prescription, OTC, herbal supplements, and vitamins. There may be a drug interaction between Prezcobix and other medications, such as alfuzosin, colchicine, rifampin, St. John’s wort, sildenafil, midazolam, lurasidone, phenytoin, ergotamine, etc. Do not use Prezcobix if you are pregnant or planning to become pregnant without informing your doctor. This drug may not work well if you take it during pregnancy. If you plan to get pregnant, ask your doctor for another antiviral medicine to use during pregnancy. HIV can be passed to your baby in pregnancy if the virus is not controlled. If you do not plan to get pregnant, ask your doctor about non-hormonal birth control to prevent pregnancy. Hormonal birth control can increase the side effects of Prezcobix.

Do not use Prezcobix while breastfeeding without talking to your doctor. It is unknown if Prezcobix passes into breast milk. Women with HIV or AIDS should not breastfeed a baby. Even if your baby is born without HIV, the virus may be passed to your baby through breast milk. Do not give this drug to children younger than three years of age or people who weigh less than 88 pounds (40 Kilograms). Use your medicine exactly as prescribed by your doctor. Take this drug once daily with food. Take this drug as prescribed without skipping doses. You can take it at the same time every day to help you remember. Do not change your dosing schedule or stop using this drug without talking to your doctor. Stopping this drug may cause the amount of virus in your body to increase and may make the infection more resistant to the drug. Prezcobix is not a cure for HIV or AIDS. The drug will not prevent you from passing HIV to other people. Do not have unprotected sex or share razors or toothbrushes. Talk with your doctor about safe ways to prevent HIV transmission during sex. Do not give this drug to another person even if they have the same symptoms as you do. Store this medication at room temperature, away from moisture and heat. Keep it out of the reach of children.

Do I need a prescription to order Prezcobix?

Yes, a prescription is required from your physician to order Prezcobix.