0

Home > Drug Category > Cancer Medications > Rozlytrek and Equivalent

Rozlytrek Information

Rozlytrek (Entrectinib) is an antineoplastic medication used to treat ROS1-positive non-small cell lung cancer (NSCLC) that has spread to other parts of the body. This medication is also used in treating adult and pediatric patients (older than 1 month) with solid tumors with a neurotrophic tyrosine receptor kinase (NTRK) gene fusion without a known acquired resistance mutation. The active ingredient in Rozlytrek is Entrectinib. A selective tyrosine kinase inhibitor such as Entrectinib works by inhibiting the kinase activity of the TRKA/B/C and ROS1 proteins, whose activating fusions drive proliferation in certain types of cancer.

Rozlytrek Side Effects

The most common side effects of Rozlytrek may include fatigue, dizziness, increased weight gain, diarrhea, nausea, vomiting, low blood volume (anemia), electrolyte derangement (low calcium and phosphate), deranged liver function, abdominal pain, and poor sleep. Call your doctor right away if you have any of the severe side effects, such as:
• Decreased appetite;
• Muscle weakness;
• Numbness or weakness of the arms and legs;
• Severe headache;
• Sudden drop in blood pressure;
• Symptoms of heart failure include difficulty with breathing, swollen legs, and recurrent cough

Rozlytrek Precautions

Do not use Rozlytrek if you are allergic to Rozlytrek or have other problems with taking this medication. Rozlytrek is a capsule, and it should be taken orally with a cup of water and with or without food, usually once daily. Swallow the capsule whole. Do not open or dissolve the capsules. If you or your child cannot swallow capsules whole, Rozlytrek capsules can be prepared as a suspension and taken or given by mouth or through a feeding tube. Follow your prescription label carefully and discuss with your doctor if there is anything you do not understand about your medication. Continue taking your medicine for as long as your doctor tells you. Do not stop taking this medicine without talking to your doctor first.

Before you start using this medication, tell your doctor about your medical history, including heart failure, heart problems such as prolonged Qt interval, liver problem, kidney disease, think you may be pregnant or plan to become pregnant, are breastfeeding, or are planning to breastfeed. Do not take Rozlytrek if you are pregnant. Rozlytrek may be harmful to an unborn baby when taken by a pregnant woman. Entrectinib passes into breast milk. There is a possibility that the baby may be affected. Do not breastfeed while using Rozlytrek. Discuss the best feeding practices for your child with your doctor. Tell your doctor about all your medications, including prescription, OTC, herbal supplements, and vitamins. There may be a drug interaction between Rozlytrek and other medications, such as Lefamulin, ketoconazole, ritonavir, and saquinavir. Store Rozlytrek tube cream at room temperature and keep it out of the reach of children.

Do I need a prescription to order Rozlytrek?

Yes, a prescription is required from your physician to order Rozlytrek.