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Home > Drug Category > Anti-coagulant > Sintrom and Equivalent

Sintrom Information

Sintrom (Acenocoumarol) belongs to a group of medicines called anticoagulants (blood thinning medicines). Sintrom is used to treat and prevent blood clots that are blocking the blood vessels e.g., deep vein thrombosis (DVT). Sintrom does not dissolve blood clots that have already formed but it may stop the clots from becoming larger and causing more serious problems. It is also used to treat atrial fibrillation (an abnormal heart rhythm) that is associated with blood clots, and to treat and prevent blood clots in the lungs. It is used along with other medications to treat blood clots in the heart and transient mini strokes. Acenocoumarol works by partially blocking the reuse of vitamin K in your liver which is needed to make clotting factors that help the blood to clot and prevent bleeding.

Sintrom Side Effects

The most common side effects of Sintrom may include diarrhea; fever; hives; itchy skin; loss of appetite; loss of hair; nausea; vomiting. Call your doctor right away if you have any of the serious side effects such as:
• Bleeding from cuts that take a long time to stop;
• Bleeding gums;
• Bleeding from various organs such as stomach, intestines, gallbladder (abdominal pain, vomiting blood, blood or tarry stools), urinary tract (backache, blood in the urine), brain (dizziness, severe headache, weakness in an arm or leg, blurred vision) and eyes;
• Headaches, dizziness, or weakness;
• Heavier than normal menstrual bleeding;
• Nosebleeds;
• Numbness or tingling of the face, hands, or feet;
• Pain, swelling, or discomfort;
• Paralysis;
• Pink or brown urine;
• Sudden shortness of breath;
• Unexplained bruising;
• Unusual pain or swelling.

Sintrom Precautions

Do not use Sintrom if you are allergic to Acenocoumarol or similar medicines used to thin the blood called coumarin derivatives (e.g. warfarin, phenprocoumon) or if you have any other medical problems, especially if you are pregnant, planning to become pregnant or breast-feeding; are an alcoholic; have any mental illness (schizophrenia or dementia); have recently had, or are about to have any major surgery; had a stroke caused by bleeding into your brain; suffer from very high blood pressure; have stomach ulcer or any intestinal bleeding; cough up blood; suffer from any bleeding disorders or unexplained bruising; feel sharp pain in the centre or left side of the chest or if you experience flu-like symptoms; have severe liver or kidney disease. Before you start taking this medication, tell your doctor about your medical history, including if you are pregnant or breast feeding; have cancer; have an infection or inflammation (swelling); a disorder affecting the absorption of food from the stomach and/or intestine; heart failure (which causes swelling and shortness of breath); have liver problems; kidney problems; have an overactive thyroid; are elderly; suffer from a blood disorder such as protein C or protein S deficiency; have a higher risk of bleeding, for example if you have a stomach or duodenal ulcer or have ever had one, high blood pressure, problems with circulation of blood to the brain, anaemia, recent wound or injury. Do not receive any injections into your muscles whilst you are taking Sintrom. Tell your doctor about all the medications you take including prescription, OTC, herbal supplements and vitamins. There may be a drug interaction between Sintrom and other medications. Be careful when drinking alcohol as it may affect how Sintrom thins your blood. Avoid drinking cranberry juice or taking other cranberry products as this could mean you do not receive the correct amount of acenocoumarol. Do not take Sintrom if you are pregnant. Sintrom, like other anticoagulants can cause serious harm to your baby. Sintrom contain lactose. If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor or pharmacist before taking this medicine.

Do I need a prescription to order Sintrom?

Yes, a prescription is required from your physician to order Sintrom.